Program
Welcome Address from the Scientific Committee
Key advances: the latest research over the last 12 months
Chairs: Quentin Anstee, Newcastle University, UK
& Arun Sanyal, Virginia Commonwealth University, USA
14:45 - 15:10
Basic Science Update
Mathias Heikenwalder, German Cancer Research Center, Germany
15:10 - 15:35
Clinical Update
Vlad Ratziu, Sorbonne University, France
15:35 - 16:00
Panel Discussion
Coffee Break, Exhibition & Poster Viewing
Chair: Michael Roden, German Center of Diabetology, Germany
Challenges and opportunities in NASH: a Big Picture Talk
Arun Sanyal, Virginia Commonwealth University, USA
Chair: Michael Roden, German Center of Diabetology, Germany
& Rifaat Safadi, Hadassah Hebrew University, Israel
17:00 - 17:10
Tumor suppressor role of the caveolar α1-Na/K-APTase signalosome in nash related hepatocellular carcinoma (HCC)
Juan Sanabria, Marshall and Case Western Reserve Universities, USA
17:10 - 17:20
Unraveling the transcriptional dynamics of NASH pathogenesis affecting atherosclerosis
Anita van den Hoek, TNO, The Netherlands
17:20 - 17:30
Beyond the fat: dysregulated glycosylation is observed in NASH and influences the immune infiltration
Jake Griner, Medical University Of South Carolina, USA
17:30 - 17:40
Specific loss of adaptation of hepatic mitochondrial respiration in non-alcoholic steatohepatitis and type 2 diabetes
Sofiya Gancheva, University Clinic Düsseldorf, Germany
17:40 - 17:50
Sarcopenia is associated with depression and fatigue in patients with non-alcoholic fatty liver disease
Anna Sheptulina, National Medical Research Center for Therapy and Preventive Medicine, Russian Federation
Chair: Michael Roden, German Center of Diabetology, Germany
& Rifaat Safadi, Hadassah Hebrew University, Israel
18:00 - 18:20
No, it is not
Naveed Sattar, University of Glasgow, UK
18:20 - 18:40
Yes, it is
Kathleen Corey, Harvard Medical School, USA
18:40 - 19:00
Open Discussion
Networking Reception, Exhibition & Poster Viewing
Chair: Rifaat Safadi, Hadassah Hebrew University, Israel
& Lawrence Serfaty, University of Strasbourg, France
08:30 - 08:50
Psychology point of view – behavioural aspects
Maya Balakrishnan, Baylor College of Medicine, USA
08:50 - 09:10
Apps to support activity and lifestyle change – the use of technology
Michael Trenell, Newcastle University, UK
09:10 - 09:30
Current state of the art: Weight loss therapy
Raluca Pais, Pitié Salpetriere Hospital, France
09:30 - 09:50
Current state of the art: Surgical weight loss
Gerhard Prager, Medical University of Vienna, Austria
09:50 - 10:00
Liver saturated fat content associates with hepatic DNA methylation in obese individuals
Ratika Sehgal, University of Eastern Finland, Finland
10:00 - 10:30
Panel Discussion
Coffee Break, Exhibition & Poster Viewing
Optimising management and prevention of end organ damage
Chairs: Vlad Ratziu, Sorbonne University, France
& Quentin Anstee, Newcastle University, UK
11:00 - 11:20
Focus on diabetes therapy
Michael Roden, German Diabetes Center, Germany
11:20 - 11:40
Focus on atherogenic dyslipidaemia
Kathleen Corey, Harvard Medical School, USA
11:40 - 12:00
Focus on chronic kidney disease
Gianluca Perseghin, Università degli Studi Milano Bicocca, Italy
12:00 - 12:10
Lanifibranor, a pan-PPAR agonist, improves markers of cardiometabolic health in patients with NASH
Michael Cooreman, France
12:10 - 12:35
Panel Discussion
Industry session not included in the main event CME/CPD credit
Lunch Break, Exhibition & Poster Viewing
Chairs: Arun Sanyal, Virginia Commonwealth University, USA
& Quentin Anstee, Newcastle University, UK
14:20 - 14:40
Evaluation of NAFLD in a large public health system (population screening)
Lawrence Serfaty, University of Strasbourg, France
14:40 - 15:00
How to identify the patients with NASH stage 2 and 3
Jerome Boursier, CHU d'Angers, France
15:00 - 15:20
How to identify patients with cirrhosis
Jörn Schattenberg, University Medical Center Mainz, Germany
15:20 - 15:40
How to identify alcohol use disorder in your patients
Philippe Mathurin, University Hospital of Lille, France
15:40 - 15:50
NAFLD and insulin resistance in type 1 diabetes. Time to expand the criteria of the metabolic syndrome?
Jonathan Mertens, University of Antwerp, Belgium
15:50 - 16:00
Significantly worse outcomes after variceal haemorrhage for cirrhosis patients with prior NASH versus those without in the TriNetX EHR database
Philip Ambery, Addenbrooke’s Hospital, Sweden
16:00 - 16:30
Panel Discussion
Coffee Break, Exhibition & Poster Viewing
Chair: Arun Sanyal, Virginia Commonwealth University, USA
Trial endpoints – balancing short-term gain with long-term pain
Quentin Anstee, Newcastle University, UK
Chair: Philippe Mathurin, University Hospital of Lille, France
& Jörn Schattenberg, University Medical Center Mainz, Germany
17:30 - 17:50
The Impact of NAFLD on COVID related outcomes
Rakhi Mailwall, Institute of Liver & Biliary Sciences, India
17:50 - 18:10
The impact of the pandemic on liver related care
Sidney Barritt, The University of North Carolina at Chapel Hill, USA
18:10 - 18:30
Impact of fatty liver disease on COVID19 vaccination
Rifaat Safadi, Hadassah Hebrew University, Israel
18:30 - 19:00
Panel Discussion
Chairs: Arun Sanyal, Virginia Commonwealth University, USA
& Michael Roden, German Center of Diabetology, Germany
08:30 - 08:50
GLP1 containing combinations – a rationale for therapies in NASH
Amalia Gastaldelli, National Research Council of Italy, Italy
08:50 - 09:10
Clinical use of GLP1 in NASH
Philip Newsome, University of Birmingham, UK
09:10 - 09:30
FGF21 Pharmacology in the context of NASH
Saswata Talukdar, CMD Discovery, USA
09:30 - 09:40
A novel positive allosteric modulator of the GABAA receptor prevents lipotoxicity-induced liver cell injury
Juergen Eckel, Institute for Clinical Diabetology, Germany
09:40 - 10:10
Panel Discussion
Coffee Break, Exhibition & Poster Viewing
Chairs: Quentin Anstee, Newcastle University, UK
& Rifaat Safadi, Hadassah Hebrew University, Israel
10:40 - 11:00
Bile Acid and bile acid conjugates
Arun Sanyal, Virginia Commonwealth University, USA
11:00 - 11:20
Thyroxine beta receptors
Stephen Harrison, Pinnacle Clinical Research, USA
11:20 - 11:40
PPAR agonists biology
Sven Francque, University of Antwerp, Belgium
11:40 - 12:00
Gut microbiota and NAFLD: gut-liver axis
Oxana Drapkina, National Medical Research Center for Therapy and Preventive Medicine, Russian Federation
12:00 - 12:10
Antagonizing sodium taurocholate co-transporting polypeptide (NTCP) on NK cells from NAFLD patients elevate their activity and mediate activated hepatic stellate cells killing
Johnny Amer, Hadassah Hospital, Israel
12:10 - 12:40
Panel Discussion
Quentin Anstee, Newcastle University, UK
Oxana Drapkina, National Medical Research Center for Therapy and Preventive Medicine, Russian Federation
Michael Roden, German Diabetes Center, Germany
Rifaat Safadi, Hadassah Hebrew University, Israel
Arun Sanyal, Virginia Commonwealth University, USA